— If only you could've known: A hobbled Ben Roethlisberger came off the bench for Pittsburgh to throw for 379 yards and three TD passes. Questionable going into the game with a sprained left foot, Roethlisberger was forced into duty when Landry Jones left with a sprained left ankle. Antonio Brown and Martavis Bryant owners got a nice surprise with Big Ben's return as both had big games.
Titans rookie running back David Cobb might get his first taste of action at Jacksonville. He was inactive last weekend after coming off the injured reserve-designated to return list this week. Tennessee sure could use a boost after Antonio Andrews had 11 carries for eight yards. Blake Bortles has thrown at least two TD passes in seven of nine games this season.
For years, Brock Osweiler has resided in the shadow of Peyton Manning.
Time to use a waiver-wire pick on Osweiler, who's owned in one percent of Yahoo fantasy leagues. After taking over for Manning in the third quarter Sunday against Kansas City, Osweiler threw for 146 yards, one touchdowns and an interception.
— Johnny Manziel, QB, Cleveland (4.4 percent of ESPN): Threw for a career-high 372 yards.
Manning,NBA Jerseys China, who's been dealing with foot and rib injuries, finished with a career-worst 0.0 passer rating Sunday. That sort of figure actually would've been preferable to what fantasy owners received — a minus-6.6 points in typical leagues.
THE INJURY FRONT
— Devin Funchess,Air Max 97 Silver Bullet For Sale, WR, Carolina (17 percent of CBS): Starting to get Cam Newton's attention.
— Jay Ajayi, RB, Miami (owned in 18 percent of Yahoo leagues): Interim coach Dan Campbell wants to get him more carries.
Another week and even more injuries to big names:
A little trivia: Osweiler ties Matt Blundin (1992-97) and Dan McGwire (1991-95) as the tallest QBs in league history, according to STATS.
Osweiler has served as Manning's understudy since being drafted in 2012. This weekend in Chicago will be a chance to show what he can do.
— New England lost another weapon as receiver Julian Edelman left with a foot injury against the New York Giants. The Patriots lost Dion Lewis last weekend,Jordan Sneakers For Sale.

— Josh Huff,Cheap Air Max Shoes, WR, Philadelphia (zero percent of Yahoo): Had three catches and a TD against Miami.
HELP WANTED
WEEK 10 OBSERVATIONS
— Zach Miller,NBA Jerseys Store, TE, Chicago (1 percent of Yahoo): Caught five passes for 107 yards and two scores against St. Louis.
Here are possible waiver additions to consider:
— Mark Sanchez, QB, Philadelphia (1 percent of Yahoo): Good insurance for Bradford.
— That Arizona passing attack sure looked potent at Seattle. Michael Floyd had two TD receptions and Larry Fitzgerald finished with 10 catches for 130 yards.
Maybe Osweiler can jump-start an offense that hasn't been able to get Demaryius Thomas rolling enough to meet his high draft position nor has found proven production from C.J. Anderson or Ronnie Hillman.
— Broncos receiver Emmanuel Sanders passed the concussion protocol, but was held out after getting hurt in the second half. Sanders played Sunday even though he missed a week of practice with a sprained left ankle. He didn't have a catch.
Manning won't even dress. Instead, Osweiler's backup will be rookie Trevor Siemian. As for when Manning might return, well, coach Gary Kubiak didn't exactly know, saying: "I told him that his total focus is going to be on (him getting healthy)."
— Philadelphia's Sam Bradford had with a concussion and injured his left shoulder. In addition, Eagles running back Ryan Mathews suffered a concussion.
Now, the 6-foot-8 quarterback gets his chance to stand tall. The Denver Broncos benched a banged-up Manning on Monday and handed the keys to the offense over to Osweiler.
— Kansas City's Charcandrick West did his best Jamaal Charles imitation, scoring once on a short run and another on a long pass play.
— Adrian Peterson looked a lot like, well, Adrian Peterson as he rushed for 203 yards and a touchdown for Minnesota.
LOOKING AHEAD TO THURSDAY